Preclinical Journey of anti-Claudin18.2 ADC for Effective Translation Into Clinical Pharmacokinetics
Time: 4:00 pm
day: Conference Day 2
Details:
- Introducing anti-Claudin18.2 ADC, preclinical studies, bioanalytical strategy and assay design for PK analysis
- Utilizing preclinical pharmacology, toxicology and animal PK data to determine safe human starting dose
- Reviewing clinical PK and correlation with human PK predictions
