Impact of ADC Stability on Safety & Translation of Preclinical Stability Data into Human PK Prediction: Species-Specific Considerations
Time: 9:30 am
day: Conference Day Two
Details:
• Defining key factors and implications of ADC instability on safety
• Exploring species differences in stability and PK, discussing ADC degradation in rodents vs. other species: Significance for model selection
• Translating preclinical stability data into human PK: Modeling approaches and predictive value
